Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2392374 | 0.81 | KCNN4 (0.69) | KCNN4KCNA3CYP11B1CYP11B2KMT2A | |
| SCHEMBL9182074 | 0.81 | KCNN4 (0.57) | KCNN4KCNA3CYP11B1CYP11B2KMT2A | |
| SCHEMBL11199996 | 0.81 | KCNN4 (0.54) | KCNN4KCNA3CYP11B1CYP11B2KMT2A | |
| SCHEMBL11204373 | 0.77 | KCNN4 (0.50) | KCNN4KCNA3CYP11B1CYP11B2 | |
| SCHEMBL9669708 | 0.76 | CYP11B1 (0.67) | KCNN4KCNA3FLT3CYP11B1CYP11B2 | |
| SCHEMBL2361042 | 0.75 | KCNN4 (0.67) | KCNN4KCNA3CYP11B1CYP11B2KMT2A | |
| SCHEMBL2403558 | 0.75 | KCNN4 (0.58) | KCNN4KCNA3CYP11B1CYP11B2TSHR | |
| SCHEMBL2391892 | 0.75 | KCNN4 (0.58) | KCNN4KCNA3CYP11B1CYP11B2KMT2A | |
| SCHEMBL20772229 | 0.75 | KCNN4 (0.58) | KCNN4KCNA3CYP11B1CYP11B2KMT2A | |
| SCHEMBL1750941 | 0.75 | KCNN4 (0.58) | KCNN4KCNA3CYP11B1CYP11B2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667868-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-23 | — | — | EP | disclosed |