Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9146813 | 0.89 | DPP4 (0.65) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9146820 | 0.89 | DPP4 (0.65) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9146376 | 0.89 | DPP4 (0.65) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10658450 | 0.84 | DPP4 (0.61) | DPP4CHRM2DRD1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL10652843 | 0.83 | DPP4 (0.60) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9044640 | 0.83 | DPP4 (0.60) | DPP4CHRM2DRD1KDM4ELMNA | |
| Trovafloxacin4 SCHEMBL9178854 | 0.83 | DPP4 (0.72) | DPP4CHRM2DRD1KDM4ELMNA | |
| Trovafloxacin4 SCHEMBL9178841 | 0.83 | DPP4 (0.72) | DPP4CHRM2DRD1KDM4ELMNA | |
| Trovafloxacin4 SCHEMBL9184555 | 0.83 | DPP4 (0.72) | DPP4CHRM2DRD1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL10655119 | 0.83 | DPP4 (0.59) | DPP4CHRM2DRD1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391763-A | 3-aza-bicyclo[3.1.0]hexanes which are intermediates for anti-bacterial azabicyclo quinolone carboxylic acids | PFIZER INC. (US) | 1995-02-21 | — | — | US | disclosed |
| US-5164402-A | Bactericides | PFIZER INC (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0413455-A2 | Azabicyclo quinolone carboxylic acids | PFIZER INC. (US) | 1991-02-20 | — | — | EP | disclosed |