Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | TOP2A | P11388 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470749 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9183152 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9198500 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9198493 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9183135 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9182284 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9184531 | 0.89 | KDM4E (0.72) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8741007 | 0.87 | KDM4E (0.67) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8741006 | 0.87 | KDM4E (0.67) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL6214751 | 0.87 | KDM4E (0.67) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413455-B1 | Azabicyclo quinolone carboxylic acids | PFIZER (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5391763-A | 3-aza-bicyclo[3.1.0]hexanes which are intermediates for anti-bacterial azabicyclo quinolone carboxylic acids | PFIZER INC. (US) | 1995-02-21 | — | — | US | disclosed |
| US-5164402-A | Bactericides | PFIZER INC (US) | 1992-11-17 | — | — | US | disclosed |
| EP-0413455-A2 | Azabicyclo quinolone carboxylic acids | PFIZER INC. (US) | 1991-02-20 | — | — | EP | disclosed |