SCHEMBL9183333

SCHEMBL9183333

ClCCc1cc(Cl)ccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.46
IDO1 P14902 4/20 0.41
CYP3A4 P08684 3/20 0.41
HIF1A Q16665 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
SLC22A1 O15245 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPT P10636 1/20 0.41
HSPD1 P10809 1/20 0.41
HSPA5 P11021 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
HTT P42858 1/20 0.41
BLM P54132 1/20 0.41
HSPE1 P61604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL81972 0.86 TP53 (0.42) TP53IDO1CYP3A4HIF1AMEN1
SCHEMBL29587149 0.81 IDO1 (0.58) TP53IDO1CYP3A4HTTSMN1; SMN2
SCHEMBL7020135 0.81 IDO1 (0.58) TP53IDO1CYP3A4HTTSMN1; SMN2
SCHEMBL937350 0.80 TP53 (0.50) TP53IDO1CYP3A4HIF1AMEN1
SCHEMBL7224195 0.79 FLT1 (0.46) TP53IDO1CYP3A4HIF1AMEN1
SCHEMBL1570136 0.79 TAAR1 (0.56) TP53IDO1TSHR
SCHEMBL3620010 0.79 TP53 (0.44) TP53IDO1CYP3A4HIF1AMEN1
SCHEMBL17552726 0.79 TP53 (0.44) TP53IDO1CYP3A4HIF1AMEN1
SCHEMBL10534385 0.79 IDO1 (0.40) TP53IDO1CYP3A4HIF1AMEN1
SCHEMBL1560923 0.79 CYP3A4 (0.45) TP53IDO1CYP3A4HIF1AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676710-B2 Industrial methods for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2017-06-13 US disclosed
US-9630919-B2 Industrial methods for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2017-04-25 US disclosed
EP-0473464-B1 Process for preparing 2-4-dichloro-3-alkyl-6-nitrophenols TAOKA CHEMICAL CO LTD (JP) 1995-06-14 EP disclosed
US-5136109-A PROCESS FOR PREPARING 2,4-DICHLORO-3-ALKYL-6-NITROPHENOLS TAOKA CHEMICAL COMPANY, LTD. (JP) 1992-08-04 US disclosed
EP-0473464-A1 Process for preparing 2-4-dichloro-3-alkyl-6-nitrophenols TAOKA CHEMICAL CO., LTD (JP) 1992-03-04 EP disclosed
US-5012015-A Nitrading a trichlorobenzene with mixed acid, hydrolysis DAIEI CHEMICAL CO., LTD. (JP) 1991-04-30 US disclosed