Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184550 | 0.82 | MEN1 (0.45) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9183369 | 0.80 | PNP (0.49) | MEN1KMT2ABLMALDH1A1LMNA | |
| SCHEMBL8839866 | 0.80 | HPRT1 (0.58) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL10970953 | 0.79 | BLM (0.66) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| Hydrochloric Acid SCHEMBL10533769 | 0.79 | HPRT1 (0.57) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9583727 | 0.78 | BLM (0.72) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL21162677 | 0.78 | PDE3A (0.55) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9184455 | 0.77 | BLM (0.61) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9182612 | 0.77 | BLM (0.61) | PDE3AMEN1KMT2ABLMALDH1A1 | |
| SCHEMBL9185885 | 0.77 | BLM (0.61) | PDE3AMEN1KMT2ABLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242482-B1 | Antiviral purine derivatives and process for their preparation | BEECHAM GROUP PLC (GB) | 1995-09-06 | — | — | EP | claimed |
| US-4965270-A | Viricides | BEECHAM GROUP P.L.C. (GB) | 1990-10-23 | — | — | US | claimed |
| EP-0313289-A2 | Process for the preparation of purine compounds and intermediates therefor | BEECHAM GROUP PLC (GB) | 1989-04-26 | — | — | EP | claimed |
| EP-0242482-A2 | Antiviral purine derivatives and process for their preparation | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | claimed |
| EP-0242482-B1 | Antiviral purine derivatives and process for their preparation | BEECHAM GROUP PLC (GB) | 1995-09-06 | — | — | EP | disclosed |
| US-4965270-A | Viricides | BEECHAM GROUP P.L.C. (GB) | 1990-10-23 | — | — | US | disclosed |
| EP-0242482-A2 | Antiviral purine derivatives and process for their preparation | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | disclosed |