SCHEMBL9184705

SCHEMBL9184705

C=C(C(=O)O)C(OC(=O)CC(C)=O)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP3 P08254 1/20 0.42
MMP9 P14780 1/20 0.42
MMP13 P45452 1/20 0.42
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
KLK7 P49862 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4339087 0.81 MGAM (0.41) MGAMGAASIMGAM2
SCHEMBL8814019 0.79 MGAM (0.43) MGAMGAASIMGAM2
SCHEMBL2127187 0.75 MGAM (0.39) MGAMGAASIMGAM2KLK7
SCHEMBL24119152 0.74 MGAM (0.50) MMP1MMP2MMP3MMP9MMP13
SCHEMBL18832136 0.74 MGAM (0.50) MMP1MMP2MMP3MMP9MMP13
Methacrylic Acid SCHEMBL29104897 0.74 MGAM (0.41) MGAMGAASIMGAM2
SCHEMBL9510655 0.73 MGAM (0.40) MGAMGAASIMGAM2
SCHEMBL944289 0.71 MGAM (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL3468723 0.71 MGAM (0.35) MGAMGAASIMGAM2
Methacrylic Acid SCHEMBL25423391 0.70 TSHR (0.39) MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0457276-B1 Unsaturated polyester resins LONZA SPA (IT) 1995-08-09 EP claimed
US-5362800-A Curable acrylates with oxoesters ALUSUISSE ITALIA S.P.A. (IT) 1994-11-08 US claimed
EP-0457276-A1 Unsaturated polyester resins LONZA S.P.A. (IT) 1991-11-21 EP claimed