Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28847641 | 0.94 | TDP1 (0.68) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL31612315 | 0.93 | TDP1 (0.71) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL29098894 | 0.93 | TDP1 (0.71) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL31612295 | 0.93 | TDP1 (0.71) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL1941975 | 0.88 | TDP1 (0.57) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL2035615 | 0.82 | TDP1 (0.67) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL28342825 | 0.81 | KMT2A (0.55) | MAPTNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL11770456 | 0.81 | NPC1 (0.54) | MAPTL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL1052631 | 0.81 | TDP1 (0.86) | TDP1MAPTL3MBTL1LMNAHDAC1 | |
| SCHEMBL7068671 | 0.81 | TDP1 (0.95) | TDP1MAPTL3MBTL1LMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642779-B | 2, 6-diaryl pyridine substance and preparation method thereof | 温州大学 | 2021-04-16 | — | — | CN | disclosed |
| CN-110642779-A | 2, 6-diaryl pyridine substance and preparation method thereof | 温州大学 | 2020-01-03 | — | — | CN | disclosed |
| EP-0530696-B1 | Process for the preparation of pentane 1,5-diamines | BASF AG (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5344983-A | Selective preparation of linear pentane-1,5-diamines in increased yields | BASF AKTIENGESELLSCHAFT (DE) | 1994-09-06 | — | — | US | disclosed |
| EP-0530696-A2 | Process for the preparation of pentane 1,5-diamines | BASF Aktiengesellschaft (DE) | 1993-03-10 | — | — | EP | disclosed |
| US-4277404-A | INTERMEDIATES FOR TRANQUILIZERS | PFIZER INC. (US) | 1981-07-07 | — | — | US | disclosed |
| US-4267331-A | REDUCTIVE ALKYLATION OF A 5-PHENYL-2,3,4,4A,5,9B-HEXAHYDRO-1H-PYRIDO/4,3-B/INDOLE WITH A REDUCING AGENT AND A 2-HYDROXY-5- OR 6-PHENYLFURAN OR -PYRAN | PFIZER INC. (US) | 1981-05-12 | — | — | US | disclosed |
| US-4252812-A | TRANQUILIZERS | PFIZER INC. (US) | 1981-02-24 | — | — | US | disclosed |
| US-4224329-A | TRANQUILIZERS | PFIZER INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-3980656-A | LOWER SERUM LIPIDS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |