Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189451 | 1.00 | LSS (0.50) | LSSKMT2ASMN1; SMN2ADAMTS4ADAMTS5 | |
| SCHEMBL9189443 | 1.00 | LSS (0.50) | LSSKMT2ASMN1; SMN2ADAMTS4ADAMTS5 | |
| SCHEMBL9182946 | 1.00 | LSS (0.50) | LSSKMT2ASMN1; SMN2ADAMTS4ADAMTS5 | |
| SCHEMBL9182954 | 1.00 | LSS (0.50) | LSSKMT2ASMN1; SMN2ADAMTS4ADAMTS5 | |
| SCHEMBL9185338 | 1.00 | LSS (0.50) | LSSKMT2ASMN1; SMN2ADAMTS4ADAMTS5 | |
| SCHEMBL9190093 | 0.99 | LSS (0.48) | LSSKMT2ASMN1; SMN2ADAMTS4ADAMTS5 | |
| SCHEMBL9190086 | 0.99 | LSS (0.48) | LSSKMT2ASMN1; SMN2ADAMTS4ADAMTS5 | |
| SCHEMBL9186428 | 0.96 | LSS (0.48) | LSSKMT2ASMN1; SMN2ADAMTS4ADAMTS5 | |
| SCHEMBL9188427 | 0.96 | LSS (0.48) | LSSKMT2ASMN1; SMN2ADAMTS4ADAMTS5 | |
| SCHEMBL9188181 | 0.96 | LSS (0.48) | LSSKMT2ASMN1; SMN2ADAMTS4ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423520-B1 | Liquid crystalline composition for the use in a twisted nematic cell | MERCK PATENT GMBH (DE) | 1995-08-02 | — | — | EP | disclosed |