Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | USP18 | Q9UMW8 | 2/20 | 0.40 |
| ▸ | UCHL5 | Q9Y5K5 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9186135 | 1.00 | KMT2A (0.55) | KMT2AMEN1HRH3CASP3METAP1 | |
| SCHEMBL6132768 | 0.86 | MEN1 (0.54) | KMT2AMEN1HRH3METAP1HSP90AA1 | |
| SCHEMBL6132766 | 0.86 | MEN1 (0.54) | KMT2AMEN1HRH3METAP1HSP90AA1 | |
| SCHEMBL8596084 | 0.86 | MEN1 (0.54) | KMT2AMEN1HRH3METAP1HSP90AA1 | |
| SCHEMBL79547 | 0.82 | MEN1 (0.66) | KMT2AMEN1HRH3MAPTALDH1A1 | |
| SCHEMBL1598877 | 0.82 | MEN1 (0.66) | KMT2AMEN1HRH3MAPTALDH1A1 | |
| SCHEMBL7362683 | 0.82 | MEN1 (0.66) | KMT2AMEN1HRH3MAPTALDH1A1 | |
| SCHEMBL8592053 | 0.80 | MEN1 (0.57) | KMT2AMEN1HRH3METAP1TDP1 | |
| SCHEMBL8411263 | 0.80 | HRH3 (0.64) | KMT2AMEN1HRH3METAP1AKR1B1 | |
| SCHEMBL8411264 | 0.80 | HRH3 (0.64) | KMT2AMEN1HRH3METAP1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672036-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994004513-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1994-03-03 | — | — | WO | disclosed |