3,5-O-Dimethylpinosylvin

3,5-O-Dimethylpinosylvin

SCHEMBL918727

COc1cc(C=Cc2ccccc2)cc(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.79
MEN1 O00255 2/20 0.79
MAPT P10636 2/20 0.79
KMT2A Q03164 2/20 0.79
USP2 O75604 1/20 0.79
ALDH1A1 P00352 1/20 0.79
TP53 P04637 1/20 0.79
CYP3A4 P08684 1/20 0.79
HPGD P15428 1/20 0.79
SMN1; SMN2 Q16637 1/20 0.79
TRPV1 Q8NER1 1/20 0.79
HSD17B10 Q99714 1/20 0.79
CYP1A1 P04798 5/20 0.74
CYP1B1 Q16678 5/20 0.74
NQO2 P16083 5/20 0.73
ABL1 P00519 4/20 0.73
BCR P11274 4/20 0.73
ESR1 P03372 3/20 0.73
ABCB1 P08183 3/20 0.73
CYP1A2 P05177 3/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,5-O-Dimethylpinosylvin SCHEMBL918726 1.00 KDM4E (0.79) KDM4EMEN1MAPTKMT2AUSP2
3,5-O-Dimethylpinosylvin SCHEMBL9419809 1.00 KDM4E (0.79) KDM4EMEN1MAPTKMT2AUSP2
3,5-O-Dimethylpinosylvin SCHEMBL6253954 0.98 KDM4E (0.76) KDM4EMEN1MAPTKMT2AUSP2
3,5-O-Dimethylpinosylvin SCHEMBL27536829 0.96 KDM4E (0.73) KDM4EMEN1MAPTKMT2AUSP2
SCHEMBL28722190 0.92 KDM4E (0.68) KDM4EMEN1MAPTKMT2AUSP2
Pterostilbene SCHEMBL3476943 0.89 NQO2 (0.86) KDM4EMEN1MAPTKMT2AUSP2
3,5-O-Dimethylpinosylvin SCHEMBL6253949 0.89 KDM4E (0.65) KDM4EMEN1MAPTKMT2AUSP2
Pterostilbene SCHEMBL3476941 0.89 NQO2 (0.86) KDM4EMEN1MAPTKMT2AUSP2
Pinosylvin Methyl Ether SCHEMBL9419826 0.88 KDM4E (1.00) KDM4EMEN1MAPTKMT2AUSP2
SCHEMBL12729855 0.88 KDM4E (0.69) KDM4EMEN1MAPTKMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113842390-B Lindera fruticosa active ingredient composition with gastric ulcer prevention and treatment effect, and preparation method and application thereof 河南中医药大学 2024-03-12 CN claimed
CN-115957285-A A Chinese medicinal granule for treating lung cancer 广东省中医院(广州中医药大学第二附属医院、广州中医药大学第二临床医学院、广东省中医药科学院) 2023-04-14 CN claimed
CN-113842390-A Lindera reflexa hemsl active ingredient composition with effect of preventing and treating gastric ulcer as well as preparation method and application thereof 河南中医药大学 2021-12-28 CN claimed
US-8013046-B2 Methods of vulcanizing elastomers using tall oil heads ARIZONA CHEMICAL COMPANY, LLC (US) 2011-09-06 US claimed
US-20110105633-A1 FUNCTIONALIZED STILBENE-POLYALKYLENE OXIDE PREPOLYMERS PROMETHEAN SURGICAL DEVICES LLC (US) 2011-05-05 US claimed
WO-2011049680-A1 CRYOSENSITIZING AGENTS FOR ENHANCEMENT OF CRYOABLATION BAUST JOHN M (US) 2011-04-28 WO claimed
EP-1373399-B1 METHODS OF VULCANIZING ELASTOMERS USING TALL OIL HEADS ARIZONA CHEM (US) 2008-09-03 EP claimed
US-20070260018-A1 Methods of vulcanizing elastomers using tall oil heads BANK OF AMERICA, N.A. 2007-11-08 US claimed
EP-1373399-A4 METHODS OF VULCANIZING ELASTOMERS USING TALL OIL HEADS ARIZONA CHEM (US) 2005-05-04 EP claimed
EP-1373399-A1 METHODS OF VULCANIZING ELASTOMERS USING TALL OIL HEADS ARIZONA CHEMICAL COMPANY (US) 2004-01-02 EP claimed
WO-2002062888-A1 METHODS OF VULCANIZING ELASTOMERS USING TALL OIL HEADS ARIZONA CHEMICAL COMPANY (US) 2002-08-15 WO claimed
US-20020028852-A1 Resveratrol analogs for prevention of disease RUTGERS, THE STATE UNIVERSITY 2002-03-07 US claimed
WO-2001021165-A1 RESVERATROL ANALOGS FOR PREVENTION OF DISEASE RUTGERS, THE STATE UNIVERSITY (US) 2001-03-29 WO claimed
US-4536332-A ISOMERIZING TRANS-DIMETHOXYSTILBENE TO CIS CONFIGURATION, DISTILLING OUT ARIZONA CHEMICAL COMPANY (US) 1985-08-20 US claimed
EP-0141271-A2 Tall oil fatty acids - quality improvement ARIZONA CHEMICAL COMPANY (US) 1985-05-15 EP claimed
CN-113842390-B Lindera fruticosa active ingredient composition with gastric ulcer prevention and treatment effect, and preparation method and application thereof 河南中医药大学 2024-03-12 CN disclosed
CN-113842390-B Lindera fruticosa active ingredient composition with gastric ulcer prevention and treatment effect, and preparation method and application thereof 河南中医药大学 2024-03-12 CN disclosed
EP-0041043-B1 PROCESS FOR THE PREPARATION OF DERIVATIVES OF ALKENYL BENZENE OR ALKENYL NAPHTHALENE CIBA-GEIGY AG (CH) 1983-11-09 EP disclosed
US-4335055-A Process for the preparation of alkenylbenzene derivatives or alkenylnaphthalene derivatives CIBA-GEIGY CORPORATION (US) 1982-06-15 US disclosed
EP-0041043-A1 Process for the preparation of derivatives of alkenyl benzene or alkenyl naphthalene CIBA-GEIGY AG (CH) 1981-12-02 EP disclosed