Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9187613 | 1.00 | LSS (0.45) | LSSHPGDALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL9187609 | 1.00 | LSS (0.45) | LSSHPGDALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL9186631 | 0.96 | LSS (0.46) | LSSHPGDALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL9186627 | 0.96 | LSS (0.46) | LSSHPGDALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL9186620 | 0.96 | LSS (0.46) | LSSHPGDALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL9188927 | 0.96 | LSS (0.47) | LSSHPGDALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL9188919 | 0.96 | LSS (0.47) | LSSHPGDALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL9188192 | 0.95 | LSS (0.48) | LSSHPGDALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL9188429 | 0.95 | LSS (0.48) | LSSHPGDALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL9188427 | 0.95 | LSS (0.48) | LSSHPGDALOX5KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423520-B1 | Liquid crystalline composition for the use in a twisted nematic cell | MERCK PATENT GMBH (DE) | 1995-08-02 | — | — | EP | disclosed |
| EP-0423520-A2 | Liquid crystalline composition for the use in a twisted nematic cell | MERCK PATENT GmbH (DE) | 1991-04-24 | — | — | EP | disclosed |