SCHEMBL9187643

SCHEMBL9187643

CCCCCCCCCCCCCCCCS(=O)(=O)Nc1cccc(NC(=O)C(Cl)(Oc2ccc(S(=O)(=O)c3ccc(O)cc3)cc2)C(=O)C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.39
▸ MAP1LC3B Q9GZQ8 1/20 0.36
▸ MAP1LC3A Q9H492 1/20 0.36
▸ ELANE P08246 1/20 0.36
▸ ADRB3 P13945 2/20 0.36
▸ ADRB2 P07550 1/20 0.36
▸ ADRB1 P08588 1/20 0.36
▸ ALDH1A1 P00352 3/20 0.36
▸ MAPT P10636 2/20 0.36
▸ NAMPT P43490 1/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ AR P10275 1/20 0.34
▸ ABCC9 O60706 1/20 0.34
▸ ABCC8 Q09428 1/20 0.34
▸ KCNJ11 Q14654 1/20 0.34
▸ KCNJ8 Q15842 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11428041 0.93 KDM4E (0.47) KDM4EADRB3ADRB2ADRB1MAPT
SCHEMBL11431592 0.91 KDM4E (0.41) KDM4EALDH1A1MAPTMEN1LMNA
SCHEMBL11432988 0.91 AR (0.49) KDM4ENAMPTMEN1LMNAKMT2A
SCHEMBL9507887 0.91 AR (0.49) KDM4ENAMPTMEN1LMNAKMT2A
SCHEMBL11426019 0.91 KDM4E (0.41) KDM4EADRB3ADRB2ADRB1ALDH1A1
SCHEMBL11432999 0.90 AR (0.41) KDM4EALDH1A1LMNAAR
SCHEMBL11276146 0.88 AR (0.45) KDM4EMEN1LMNAKMT2AAR
SCHEMBL11176255 0.87 NR1H4 (0.42) ALDH1A1
SCHEMBL11441585 0.87 NR1H4 (0.42) ALDH1A1
SCHEMBL11424912 0.87 AR (0.52) KDM4ENAMPTMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436249-B1 Photographic emulsions sensitized by the introduction of oligomers EASTMAN KODAK CO (US) 1995-09-13 — — EP disclosed
EP-0436249-A1 Photographic emulsions sensitized by the introduction of oligomers EASTMAN KODAK COMPANY (US) 1991-07-10 — — EP disclosed
US-5024931-A Face centered cubic crystal lattice structure, group 8 metal ion of period 5 or 6 EASTMAN KODAK COMPANY (US) 1991-06-18 — — US disclosed
US-RE30211-E COLORED IMAGES OF IMPROVED GRAININESS EASTMAN KODAK COMPANY (US) 1980-02-12 — — US disclosed
US-3933501-A Photographic elements containing color-forming couplers having and inhibiting effect upon the reactivity of competing couplers EASTMAN KODAK COMPANY (US) 1976-01-20 — — US disclosed
Send feedback