Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19023810 | 0.86 | KMT2A (0.61) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL1130501 | 0.86 | KMT2A (0.61) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| Benzoguanamine SCHEMBL3627859 | 0.84 | ADORA2A (0.83) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL13996091 | 0.82 | KMT2A (0.57) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| Hydrochloric Acid SCHEMBL30612906 | 0.82 | HRH4 (0.47) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL25352193 | 0.81 | ADORA2A (0.58) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| SCHEMBL8524606 | 0.80 | ADORA2A (0.62) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| Benzoguanamine SCHEMBL28634836 | 0.80 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| Benzoguanamine SCHEMBL27898 | 0.80 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2BPOLB | |
| Benzoguanamine SCHEMBL917182 | 0.80 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470050-B1 | Process for the preparation of 2-amino-4-alkoxy-s-triazines | CIBA GEIGY AG (CH) | 1995-11-02 | — | — | EP | disclosed |
| EP-0470050-A1 | Process for the preparation of 2-amino-4-alkoxy-s-triazines | CIBA-GEIGY AG (CH) | 1992-02-05 | — | — | EP | disclosed |
| US-5075443-A | Preparation of 2-amino-4-alkoxy-s-triazines | CIBA-GEIGY CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |