Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9184418 | 1.00 | SCN9A (0.40) | SCN9APPARDFFAR1PARP10PARP15 | |
| SCHEMBL9190078 | 1.00 | SCN9A (0.40) | SCN9APPARDFFAR1PARP10PARP15 | |
| SCHEMBL9186609 | 1.00 | SCN9A (0.40) | SCN9APPARDFFAR1PARP10PARP15 | |
| SCHEMBL9184429 | 1.00 | SCN9A (0.40) | SCN9APPARDFFAR1PARP10PARP15 | |
| SCHEMBL9186603 | 1.00 | SCN9A (0.40) | SCN9APPARDFFAR1PARP10PARP15 | |
| SCHEMBL7913376 | 0.99 | SCN9A (0.41) | SCN9APPARDFFAR1PARP10PARP15 | |
| SCHEMBL7913377 | 0.99 | SCN9A (0.41) | SCN9APPARDFFAR1PARP10PARP15 | |
| SCHEMBL9188430 | 0.97 | SCN9A (0.38) | SCN9APPARDFFAR1PARP10PARP15 | |
| SCHEMBL9188436 | 0.97 | SCN9A (0.38) | SCN9APPARDFFAR1PARP10PARP15 | |
| SCHEMBL9189936 | 0.97 | SCN9A (0.38) | SCN9APPARDFFAR1PARP10PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423520-B1 | Liquid crystalline composition for the use in a twisted nematic cell | MERCK PATENT GMBH (DE) | 1995-08-02 | — | — | EP | disclosed |
| EP-0423520-A2 | Liquid crystalline composition for the use in a twisted nematic cell | MERCK PATENT GmbH (DE) | 1991-04-24 | — | — | EP | disclosed |