Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185037 | 0.89 | GAA (0.50) | GAASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL9188426 | 0.88 | GAA (0.42) | GAASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL9189996 | 0.83 | GAA (0.45) | GAASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL9185660 | 0.82 | CYP1A2 (0.45) | GAASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL9188454 | 0.76 | GAA (0.47) | GAASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL7935900 | 0.73 | GAA (0.41) | GAASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL9185010 | 0.72 | — | — | |
| SCHEMBL9190333 | 0.72 | GAA (0.43) | GAASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL9188027 | 0.72 | CYP1A2 (0.44) | GAASMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL7934702 | 0.71 | ATM (0.43) | GAASMN1; SMN2NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469462-B1 | 2-Amino-(fluoroalkoxy-1,3,5-triazines) and method for their preparation | BASF AG (DE) | 1995-10-11 | — | — | EP | disclosed |
| US-5342939-A | 2-amino-4-fluoroalkoxy-1,3,5-triazines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |
| US-5214143-A | 2-AMINO-4-FLUOROALKOXY-1,3,5-TRIAZINES AND THE PREPARATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | disclosed |
| EP-0469462-A1 | 2-Amino-(fluoroalkoxy-1,3,5-triazines) and method for their preparation | BASF Aktiengesellschaft (DE) | 1992-02-05 | — | — | EP | disclosed |