Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD5 | P21918 | 2/20 | 0.44 |
| ▸ | HRH2 | P25021 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637472 | 0.85 | CYP19A1 (0.44) | EPHX2CYP19A1CNR1 | |
| SCHEMBL6699187 | 0.80 | CYP19A1 (0.49) | CYP19A1HTR2AHRH1CACNA1C | |
| SCHEMBL23126408 | 0.79 | EPHX2 (0.51) | EPHX2CYP19A1CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL8411269 | 0.78 | EPHX2 (0.58) | EPHX2CYP19A1CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL1349663 | 0.76 | KDM4E (0.48) | EPHX2CYP19A1CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL5948050 | 0.75 | EPHX2 (1.00) | EPHX2CYP2C9CYP2C19CYP2J2 | |
| SCHEMBL13813062 | 0.75 | CA12 (0.46) | EPHX2CYP19A1MAOAMAOBKDM4E | |
| SCHEMBL13891122 | 0.74 | CA12 (0.41) | EPHX2CYP19A1KDM4E | |
| SCHEMBL12444126 | 0.74 | — | — | |
| SCHEMBL39936 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674626-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | ORION-YHTYMÄ OY (FI) | 1995-10-04 | — | — | EP | disclosed |