SCHEMBL9191908

SCHEMBL9191908

CO[Si](OC)(OC)C(C)CCNC(=O)OC(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.53
GAA P10253 1/20 0.53
KMT2A Q03164 1/20 0.53
TDP1 Q9NUW8 1/20 0.47
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA12 O43570 2/20 0.40
CA9 Q16790 2/20 0.40
EPHX1 P07099 1/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CA7 P43166 1/20 0.39
KCNA5 P22460 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GFER P55789 1/20 0.39
CTSK P43235 2/20 0.39
MALT1 Q9UDY8 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3478212 0.84 EPHX1 (0.42) MEN1GAAKMT2AEPHX1KCNA5
SCHEMBL21773371 0.80 CASR (0.35) MEN1GAAKMT2AEPHX1ALDH1A1
SCHEMBL397759 0.80 MEN1 (0.61) MEN1GAAKMT2ATDP1MAOA
SCHEMBL19866718 0.79 MEN1 (0.56) MEN1GAAKMT2ATDP1MAOA
SCHEMBL5761580 0.79 MEN1 (0.59) MEN1GAAKMT2ATDP1MAOA
SCHEMBL12598786 0.79 MEN1 (0.59) MEN1GAAKMT2ATDP1MAOA
SCHEMBL2368382 0.79 MEN1 (0.59) MEN1GAAKMT2ATDP1MAOA
SCHEMBL4540745 0.79 CYP2D6 (0.39) MEN1GAAKMT2AALDH1A1LMNA
SCHEMBL8026936 0.78 MEN1 (0.54) MEN1GAAKMT2ATDP1MAOA
SCHEMBL1262487 0.78 MEN1 (0.54) MEN1GAAKMT2ATDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5220047-A CARBAMATE SILICON COMPOUNDS AS LATENT COUPLING AGENTS AND PROCESS FOR PREPARATION AND USE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-06-15 US claimed
EP-0476564-B1 Latent carbamate silicon coupling agents and process for preparation and use OSI SPECIALTIES INC (US) 1995-12-27 EP disclosed
US-5322873-A Carbamate silicon compounds as latent coupling agents and process for preparation and use OSI SPECIALTIES, INC. (US) 1994-06-21 US disclosed
US-5220047-A CARBAMATE SILICON COMPOUNDS AS LATENT COUPLING AGENTS AND PROCESS FOR PREPARATION AND USE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-06-15 US disclosed
EP-0476564-A1 Latent carbamate silicon coupling agents and process for preparation and use OSi Specialties, Inc. (US) 1992-03-25 EP disclosed