Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | KRAS | P01116 | 1/20 | 0.60 |
| ▸ | NQO1 | P15559 | 1/20 | 0.59 |
| ▸ | NQO2 | P16083 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.57 |
| ▸ | TUBB | P07437 | 5/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192013 | 1.00 | MEN1 (0.76) | MEN1KMT2APOLBKRASNQO1 | |
| SCHEMBL9188398 | 0.89 | TUBB1 (0.65) | MEN1KMT2APOLBKRASAKR1C3 | |
| SCHEMBL16331262 | 0.89 | MEN1 (0.60) | MEN1KMT2APOLBKRASNQO1 | |
| SCHEMBL16331264 | 0.89 | MEN1 (0.60) | MEN1KMT2APOLBKRASNQO1 | |
| SCHEMBL9188390 | 0.89 | TUBB1 (0.65) | MEN1KMT2APOLBKRASAKR1C3 | |
| SCHEMBL16331265 | 0.89 | MEN1 (0.60) | MEN1KMT2APOLBKRASNQO1 | |
| SCHEMBL3044137 | 0.87 | MEN1 (0.74) | MEN1KMT2APOLBKRASAKR1C3 | |
| SCHEMBL619542 | 0.87 | TUBB1 (0.61) | MEN1KMT2APOLBKRASNQO1 | |
| SCHEMBL3044134 | 0.87 | MEN1 (0.74) | MEN1KMT2APOLBKRASAKR1C3 | |
| SCHEMBL3047079 | 0.86 | AKR1C3 (0.72) | MEN1KMT2APOLBNQO2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702436-B | Application of piperlonguminine compound in preparation of medicines for treating schistosomiasis japonica and pharmaceutical composition | 赣南师范大学 | 2023-07-14 | — | — | CN | disclosed |
| US-8921614-B1 | Selective deoxygenation of hydroxybenzaldehydes | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-12-30 | — | — | US | disclosed |
| US-5430062-A | Combretastatin analogues; inhibition of tubulin polymerization and colchicine binding; antitumor,-mitotic and -neoplastic agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-07-04 | — | — | US | disclosed |
| EP-0641301-A1 | STILBENE DERIVATIVES AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993023357-A1 | STILBENE DERIVATIVES AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-11-25 | — | — | WO | disclosed |