Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.53 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9284395 | 0.87 | BAZ2B (0.50) | BAZ2BBAZ2AALDH1A1KMT2AGAA | |
| SCHEMBL4544349 | 0.84 | BAZ2B (0.62) | BAZ2BBAZ2AALDH1A1KMT2AGAA | |
| SCHEMBL16364739 | 0.82 | BAZ2B (0.56) | BAZ2BBAZ2AALDH1A1KMT2AGAA | |
| SCHEMBL3113139 | 0.81 | BAZ2B (0.54) | BAZ2BBAZ2AALDH1A1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL5546234 | 0.79 | BAZ2B (0.53) | BAZ2BBAZ2AALDH1A1KMT2AGAA | |
| SCHEMBL9908199 | 0.79 | BAZ2B (0.57) | BAZ2BBAZ2AALDH1A1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL7377017 | 0.79 | BAZ2B (0.53) | BAZ2BBAZ2AALDH1A1KMT2AGAA | |
| SCHEMBL5710422 | 0.78 | DAO (0.53) | ALDH1A1KMT2AGAAMEN1LMNA | |
| SCHEMBL9191438 | 0.77 | BAZ2B (0.45) | BAZ2BBAZ2AALDH1A1KMT2AMEN1 | |
| SCHEMBL9191440 | 0.77 | BAZ2B (0.45) | BAZ2BBAZ2AALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538528-A1 | PYRROLE AMIDES AS ALPHA V INTEGRIN INHIBITORS | Bristol-Myers Squibb Company (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089360-A1 | PYRROLE AMIDES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |
| EP-0434070-B1 | Pyrrolealdehyde derivative | MITSUBISHI CHEM CORP (JP) | 1995-08-09 | — | — | EP | disclosed |
| US-5153217-A | Antiiipemic, anticholesterol agents | MITSUBISHI KASEI CORPORATION (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0434070-A2 | Pyrrolealdehyde derivative | Mitsubishi Chemical Corporation (JP) | 1991-06-26 | — | — | EP | disclosed |
| EP-0068460-A1 | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO. INC. (US) | 1983-01-05 | — | — | EP | disclosed |