SCHEMBL9192191

SCHEMBL9192191

C[Si](C)(C)CCCCCCOS(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.46
FNTB P49356 2/20 0.46
TSHR P16473 2/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MMP9 P14780 1/20 0.39
ALOX15 P16050 1/20 0.39
CA1 P00915 14/20 0.38
CA2 P00918 14/20 0.38
CA9 Q16790 13/20 0.38
CA12 O43570 5/20 0.38
CA7 P43166 5/20 0.38
CA14 Q9ULX7 5/20 0.38
CA3 P07451 4/20 0.38
CA4 P22748 4/20 0.38
CA6 P23280 4/20 0.38
CA5A P35218 4/20 0.38
CA5B Q9Y2D0 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3256562 1.00 FNTA (0.46) FNTAFNTBTSHRKDM4EUSP2
SCHEMBL29290534 0.91 FNTA (0.41) FNTAFNTBTSHRKDM4EUSP2
SCHEMBL17469809 0.82 FNTA (0.35) FNTAFNTBCA2
SCHEMBL27576132 0.82 FNTA (0.53) FNTAFNTBTSHRKDM4EUSP2
SCHEMBL5788200 0.82 FNTA (0.53) FNTAFNTBTSHRKDM4EUSP2
SCHEMBL721222 0.82 FNTA (0.53) FNTAFNTBTSHRKDM4EUSP2
SCHEMBL1712192 0.82 FNTA (0.53) FNTAFNTBTSHRKDM4EUSP2
SCHEMBL10787503 0.81 TSHR (0.65) TSHRKDM4EUSP2ALDH1A1LMNA
SCHEMBL17456468 0.80 FNTA (0.34) FNTAFNTB
SCHEMBL3258929 0.80 FNTA (0.41) FNTAFNTBTSHRKDM4EUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5430166-A Silanes with hydrophilic groups, their synthesis and use as surfactants in aqueous media TH. GOLDSCHMIDT AG (DE) 1995-07-04 US disclosed