SCHEMBL9192246

SCHEMBL9192246

CCCn1c2ccccc2c2cc(C=NN(c3ccccc3)c3ccccc3)ccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.53
POLB P06746 4/20 0.53
HTT P42858 2/20 0.53
PKM P14618 1/20 0.53
SRC P12931 4/20 0.51
ALDH1A1 P00352 8/20 0.51
HPGD P15428 7/20 0.51
SMN1; SMN2 Q16637 6/20 0.51
MAPT P10636 5/20 0.51
LMNA P02545 4/20 0.51
USP2 O75604 1/20 0.51
TSHR P16473 1/20 0.51
CASP1 P29466 1/20 0.51
HSD17B10 Q99714 1/20 0.51
MEN1 O00255 7/20 0.47
KMT2A Q03164 7/20 0.47
PTGER4 P35408 1/20 0.45
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13329109 1.00 KDM4E (0.53) KDM4EPOLBHTTPKMSRC
SCHEMBL9193066 0.93 KDM4E (0.51) KDM4EPOLBHTTPKMSRC
SCHEMBL9192442 0.92 CNR2 (0.51) KDM4EPOLBHTTPKMSRC
SCHEMBL9189005 0.91 CNR2 (0.50) KDM4EPOLBHTTPKMSRC
SCHEMBL29709939 0.90 KDM4E (0.66) KDM4EPOLBHTTPKMSRC
SCHEMBL332438 0.90 KDM4E (0.66) KDM4EPOLBHTTPKMSRC
SCHEMBL170206 0.90 KDM4E (0.66) KDM4EPOLBHTTPKMSRC
SCHEMBL14018376 0.88 KDM4E (0.48) KDM4EPOLBHTTPKMSRC
SCHEMBL14196892 0.87 CNR2 (0.47) KDM4EPOLBHTTPKMSRC
SCHEMBL14196939 0.86 CNR2 (0.46) KDM4EPOLBHTTPKMSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0390196-B1 Electrophotosensitive material MITA INDUSTRIAL CO LTD (JP) 1995-09-20 EP disclosed
US-5059503-A Used for copying machine MITA INDUSTRIAL CO., LTD. (JP) 1991-10-22 US disclosed
EP-0390196-A2 Electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1990-10-03 EP disclosed