Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MERTK | Q12866 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714746 | 0.91 | MEN1 (0.54) | MAPK1TSHRMERTKCA1CA2 | |
| SCHEMBL9362733 | 0.90 | TSHR (0.51) | MAPK1TSHRMERTKCA1CA2 | |
| SCHEMBL10509625 | 0.88 | TSHR (0.50) | MAPK1TSHRMERTKCA1CA2 | |
| SCHEMBL11152258 | 0.86 | TSHR (0.61) | MAPK1TSHRMERTKCA1CA2 | |
| SCHEMBL25254710 | 0.86 | TSHR (0.47) | MAPK1TSHRMERTKCA1CA2 | |
| SCHEMBL1629413 | 0.85 | MAPK1 (0.58) | MAPK1TSHRMERTKCA1CA2 | |
| SCHEMBL30310607 | 0.85 | MAPK1 (0.58) | MAPK1TSHRMERTKCA1CA2 | |
| SCHEMBL2033404 | 0.84 | TSHR (0.50) | MAPK1TSHRMERTKCA1CA2 | |
| SCHEMBL30317918 | 0.84 | TSHR (0.50) | MAPK1TSHRMERTKCA1CA2 | |
| SCHEMBL28489639 | 0.84 | TSHR (0.50) | MAPK1TSHRMERTKCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276132-A | Polyamic acid or polyimide having a steroidal skeleton providing a pretilt angle of 3 to 90 degrees; SBE(super twisted birefringence effect) and SH(super homeotropic) devices | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1994-01-04 | — | — | US | claimed |
| EP-0503918-B1 | Liquid crystal aligning agent and aligning agent-applied liquid crystal display device | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1995-12-27 | — | — | EP | disclosed |
| US-5276132-A | Polyamic acid or polyimide having a steroidal skeleton providing a pretilt angle of 3 to 90 degrees; SBE(super twisted birefringence effect) and SH(super homeotropic) devices | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0325892-B1 | PROCESS FOR THE PREPARATION OF HALOGENATED PRIMARY AMINES | CIBA-GEIGY AG (CH) | 1993-02-03 | — | — | EP | disclosed |
| WO-1992015919-A1 | LIQUID CRYSTAL ALIGNING AGENT AND ALIGNING AGENT-APPLIED LIQUID CRYSTAL DISPLAY DEVICE | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-09-17 | — | — | WO | disclosed |
| EP-0503918-A1 | Liquid crystal aligning agent and aligning agent-applied liquid crystal display device | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0473552-A1 | Process for the preparation of halogenated aromatic primary amines | CIBA-GEIGY AG (CH) | 1992-03-04 | — | — | EP | disclosed |
| US-4960936-A | Process for the preparation of halogenated aromatic primary amines | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| EP-0325892-A2 | Process for the preparation of halogenated primary amines | CIBA-GEIGY AG (CH) | 1989-08-02 | — | — | EP | disclosed |