Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192106 | 0.96 | KMT2A (0.58) | KMT2APTGS1PTGS2ABCB11ALDH1A1 | |
| SCHEMBL9193200 | 0.86 | PTGS1 (0.63) | KMT2APTGS1ALDH1A1CYP19A1 | |
| SCHEMBL9194318 | 0.86 | PTGS1 (0.55) | KMT2APTGS1PTGS2CYP19A1 | |
| SCHEMBL9197663 | 0.85 | PTGS1 (0.47) | KMT2APTGS1PTGS2CYP19A1 | |
| SCHEMBL9192631 | 0.85 | PTGS1 (0.47) | KMT2APTGS1CYP19A1 | |
| SCHEMBL9195197 | 0.85 | PTGS1 (0.66) | KMT2APTGS1PTGS2CYP19A1 | |
| SCHEMBL13943050 | 0.81 | PTGS1 (0.43) | KMT2APTGS1ALDH1A1CYP19A1 | |
| SCHEMBL13483248 | 0.81 | KMT2A (0.47) | KMT2APTGS1ALDH1A1CYP19A1 | |
| SCHEMBL9191850 | 0.79 | PTGS1 (0.53) | PTGS1CYP19A1 | |
| SCHEMBL9193415 | 0.78 | CYP19A1 (0.49) | PTGS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423482-B1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1995-01-11 | — | — | EP | claimed |
| US-5094681-A | HERBICIDAL 5H-FURAN-2-ONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | claimed |
| EP-0423482-A1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1991-04-24 | — | — | EP | claimed |
| EP-0423482-B1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1995-01-11 | — | — | EP | disclosed |
| US-5207817-A | Heterocyclic amine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | disclosed |
| US-5094681-A | HERBICIDAL 5H-FURAN-2-ONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| EP-0423482-A1 | 5H-furan-2-one derivatives | BAYER AG (DE) | 1991-04-24 | — | — | EP | disclosed |