Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9192374 | 1.00 | RARB (0.49) | RARBS1PR1S1PR3FFAR4RARA | |
| SCHEMBL9193816 | 1.00 | RARB (0.49) | RARBS1PR1S1PR3FFAR4RARA | |
| SCHEMBL9193813 | 1.00 | RARB (0.49) | RARBS1PR1S1PR3FFAR4RARA | |
| SCHEMBL9193783 | 1.00 | RARB (0.49) | RARBS1PR1S1PR3FFAR4RARA | |
| SCHEMBL9191627 | 1.00 | RARB (0.49) | RARBS1PR1S1PR3FFAR4RARA | |
| SCHEMBL9193600 | 1.00 | RARB (0.49) | RARBS1PR1S1PR3FFAR4RARA | |
| SCHEMBL9193949 | 1.00 | RARB (0.49) | RARBS1PR1S1PR3FFAR4RARA | |
| SCHEMBL9193780 | 1.00 | RARB (0.49) | RARBS1PR1S1PR3FFAR4RARA | |
| SCHEMBL9193953 | 1.00 | RARB (0.49) | RARBS1PR1S1PR3FFAR4RARA | |
| SCHEMBL9192378 | 1.00 | RARB (0.49) | RARBS1PR1S1PR3FFAR4RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394906-B1 | Liquid crystalline composition | MERCK PATENT GMBH (DE) | 1995-12-20 | — | — | EP | disclosed |
| EP-0394906-A2 | Liquid crystalline composition | MERCK PATENT GmbH (DE) | 1990-10-31 | — | — | EP | disclosed |