Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.63 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.63 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10396089 | 1.00 | CHRM2 (0.63) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9194301 | 1.00 | CHRM2 (0.63) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10394827 | 0.98 | CHRM2 (0.65) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10394825 | 0.98 | CHRM2 (0.65) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10395604 | 0.84 | CHRM2 (0.58) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10395605 | 0.84 | CHRM2 (0.58) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL10395610 | 0.84 | CHRM2 (0.58) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9189399 | 0.82 | CHRM2 (0.60) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9189392 | 0.82 | CHRM2 (0.60) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9191865 | 0.82 | CHRM2 (0.60) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937235-A | Anticholinergic agents | AMERICAN CYANAMID COMPANY (US) | 1990-06-26 | — | — | US | claimed |
| EP-0381984-B1 | 3- or 4-substituted oxotremorine derivatives | AMERICAN CYANAMID CO (US) | 1995-04-19 | — | — | EP | disclosed |
| US-5089518-A | 3- or 4-substituted oxotremorine derivatives and a method of treating cholinergic dysfunction therewith | AMERICAN CYANAMID COMPANY (US) | 1992-02-18 | — | — | US | disclosed |
| US-4952600-A | TREATING DISORDERS OF THE CENTRAL NERVOUS SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1990-08-28 | — | — | US | disclosed |
| EP-0381984-A1 | 3- or 4-substituted oxotremorine derivatives | AMERICAN CYANAMID COMPANY (US) | 1990-08-16 | — | — | EP | disclosed |
| US-4937235-A | Anticholinergic agents | AMERICAN CYANAMID COMPANY (US) | 1990-06-26 | — | — | US | disclosed |