Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 2/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | CPA3 | P15088 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17517216 | 0.91 | TDP1 (1.00) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL22151 | 0.91 | TDP1 (1.00) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL16925719 | 0.91 | TDP1 (1.00) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL165643 | 0.91 | TDP1 (1.00) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| Hydrochloric Acid SCHEMBL8841253 | 0.88 | TDP1 (0.93) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL1318745 | 0.88 | TDP1 (0.93) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL269896 | 0.88 | TDP1 (0.93) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL9678882 | 0.88 | TDP1 (0.93) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL9355977 | 0.88 | TDP1 (0.93) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 | |
| SCHEMBL8078228 | 0.88 | TDP1 (0.93) | TDP1SMN1; SMN2SLC22A6FOLH1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443352-B1 | Polyimides end-capped with diaryl substituted acetylene | NAT STARCH CHEM INVEST (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5138028-A | Composites, molding materials, adhesives, electronics | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| EP-0443352-A2 | Polyimides end-capped with diaryl substituted acetylene | National Starch and Chemical Investment Holding Corporation (US) | 1991-08-28 | — | — | EP | disclosed |