Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 15/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 3/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | NPY4R | P50391 | 3/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195749 | 1.00 | NPY1R (0.47) | NPY1RKDM4ECYP3A4GAAALOX15 | |
| SCHEMBL9201332 | 0.94 | NPY1R (0.47) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL9201322 | 0.94 | NPY1R (0.47) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL9198360 | 0.88 | NPY1R (0.49) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL9198348 | 0.88 | NPY1R (0.49) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL9194665 | 0.88 | NPY1R (0.50) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL9194672 | 0.88 | NPY1R (0.50) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL9199479 | 0.86 | NPY1R (0.51) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL9199470 | 0.86 | NPY1R (0.51) | NPY1RNPFFR1NPFFR2NPY5RNPY4R | |
| SCHEMBL9203188 | 0.86 | NPY1R (0.62) | NPY1RNPFFR1NPFFR2NPY5RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |