Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200225 | 0.94 | MAPK1 (0.50) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL9196863 | 0.93 | MAPK1 (0.49) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL9199898 | 0.93 | MAPK1 (0.55) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL9199871 | 0.92 | MAPK1 (0.52) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL9196919 | 0.88 | MAPK1 (0.58) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL29456993 | 0.85 | MAPK1 (0.55) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL9198223 | 0.85 | MAPK1 (0.55) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL9199116 | 0.83 | KMT2A (0.48) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL9206336 | 0.83 | MAPK1 (0.64) | MAPK1HSD17B10KMT2AMEN1NPC1 | |
| SCHEMBL9200751 | 0.83 | KMT2A (0.50) | MAPK1HSD17B10KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |
| EP-0497816-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN. | UNIROYAL CHEMICAL LTD (CA) | 1992-08-12 | — | — | EP | claimed |
| WO-1991005761-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-05-02 | — | — | WO | claimed |
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | disclosed |
| US-5268389-A | Containing a benzene ring | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1993-12-07 | — | — | US | disclosed |