Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | VNN1 | O95497 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380408 | 0.84 | CYP19A1 (0.42) | SMN1; SMN2CYP19A1CYP17A1KCNA5VNN1 | |
| SCHEMBL13971463 | 0.84 | CYP19A1 (0.71) | SMN1; SMN2CYP19A1CYP17A1KCNA5LMNA | |
| SCHEMBL1378201 | 0.82 | CYP19A1 (0.51) | CYP19A1CYP17A1KCNA5KCNH2VNN1 | |
| SCHEMBL1240925 | 0.82 | CYP19A1 (0.51) | SMN1; SMN2CYP19A1CYP17A1KCNA5KCNH2 | |
| SCHEMBL28242040 | 0.81 | CYP19A1 (0.54) | SMN1; SMN2CYP19A1CYP17A1KCNA5KCNH2 | |
| SCHEMBL18595855 | 0.81 | CYP19A1 (0.54) | CYP19A1CYP17A1KCNA5KCNH2VNN1 | |
| SCHEMBL30961611 | 0.80 | TSHR (0.48) | SMN1; SMN2TSHRMGLL | |
| SCHEMBL1507787 | 0.80 | TSHR (0.48) | SMN1; SMN2TSHRMGLL | |
| SCHEMBL1381350 | 0.80 | CYP19A1 (0.49) | CYP19A1CYP17A1KCNA5KCNH2VNN1 | |
| SCHEMBL1381261 | 0.80 | CYP19A1 (0.49) | CYP19A1CYP17A1KCNA5KCNH2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471259-B1 | Phenylsulfonamid substituted pyridinealken- and aminooxyalkan-carboxylic-acid derivatives | BAYER AG (DE) | 1995-05-17 | — | — | EP | disclosed |
| US-5185348-A | Inhibit platelet aggregation | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | disclosed |
| US-5155121-A | Anticoagulants, antiischemic agent | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-13 | — | — | US | disclosed |
| EP-0471259-A1 | Phenylsulfonamid substituted pyridinealken- and aminooxyalkan-carboxylic-acid derivatives | BAYER AG (DE) | 1992-02-19 | — | — | EP | disclosed |