Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.48 |
| ▸ | DPP4 | P27487 | 5/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197910 | 1.00 | PTPN1 (0.48) | PTPN1DPP4CYP1A1CYP1B1LMNA | |
| SCHEMBL7185790 | 0.99 | PTPN1 (0.49) | PTPN1DPP4CYP1A1CYP1B1LMNA | |
| SCHEMBL7185789 | 0.99 | PTPN1 (0.49) | PTPN1DPP4CYP1A1CYP1B1LMNA | |
| SCHEMBL7184945 | 0.96 | PTPN1 (0.50) | PTPN1DPP4CYP1A1CYP1B1LMNA | |
| SCHEMBL7184940 | 0.96 | PTPN1 (0.50) | PTPN1DPP4CYP1A1CYP1B1LMNA | |
| SCHEMBL7183889 | 0.95 | PTPN1 (0.52) | PTPN1DPP4CYP1A1CYP1B1LMNA | |
| SCHEMBL7183885 | 0.95 | PTPN1 (0.52) | PTPN1DPP4CYP1A1CYP1B1LMNA | |
| SCHEMBL7191563 | 0.92 | DPP4 (0.49) | PTPN1DPP4CYP1A1CYP1B1ABCG2 | |
| SCHEMBL7191561 | 0.92 | DPP4 (0.49) | PTPN1DPP4CYP1A1CYP1B1ABCG2 | |
| SCHEMBL7190701 | 0.90 | PTPN1 (0.60) | PTPN1DPP4ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |