Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184361 | 0.96 | KDM4E (0.41) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7184353 | 0.96 | KDM4E (0.41) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7182365 | 0.95 | PTPN1 (0.49) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7182372 | 0.95 | PTPN1 (0.49) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7186043 | 0.88 | MAOB (0.42) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7186039 | 0.88 | MAOB (0.42) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7183992 | 0.87 | PTPN1 (0.52) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7183999 | 0.87 | PTPN1 (0.52) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7185304 | 0.87 | ABCG2 (0.42) | PTPN1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7185312 | 0.87 | ABCG2 (0.42) | PTPN1KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |