Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ABHD11 | Q8NFV4 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9454551 | 0.88 | ADORA2A (0.50) | L3MBTL1LMNAADORA2AADORA2BADORA3 | |
| SCHEMBL9199713 | 0.87 | ADORA2A (0.57) | L3MBTL1LMNAADORA2AADORA2BADORA3 | |
| SCHEMBL9199707 | 0.87 | ADORA2A (0.57) | L3MBTL1LMNAADORA2AADORA2BADORA3 | |
| SCHEMBL9199780 | 0.82 | NPC1 (0.54) | L3MBTL1LMNAADORA2AADORA2BADORA3 | |
| SCHEMBL9199652 | 0.81 | ADORA2A (0.81) | L3MBTL1LMNAADORA2AADORA2BADORA3 | |
| SCHEMBL9199146 | 0.81 | ADORA2A (0.81) | L3MBTL1LMNAADORA2AADORA2BADORA3 | |
| SCHEMBL9199656 | 0.81 | ADORA2A (0.81) | L3MBTL1LMNAADORA2AADORA2BADORA3 | |
| SCHEMBL9193574 | 0.81 | ADORA2A (0.81) | L3MBTL1LMNAADORA2AADORA2BADORA3 | |
| SCHEMBL22767740 | 0.81 | ADORA2A (0.47) | L3MBTL1LMNAADORA2AADORA2BADORA3 | |
| SCHEMBL9199141 | 0.81 | ADORA2A (0.81) | L3MBTL1LMNAADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299209-B1 | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0387196-B1 | Complexes with optically active ligands, process for their preparation and their use | CIBA GEIGY AG (CH) | 1995-05-03 | — | — | EP | disclosed |
| US-5296490-A | Pharmaceutically useful pyrazolopyridines | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| US-5179103-A | Diuretics, hypotensive agents | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5102878-A | Treating psychological, bone, cardiovascular, blood disorders | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| US-5102869-A | Urogenital disorders | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| US-5087629-A | Diuretics, hypotensive agents; cardiotonic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| US-4994453-A | Treating asthma, diabetes, obesity, immunosuppression | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0387196-A1 | Complexes with optically active ligands, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1990-09-12 | — | — | EP | disclosed |
| US-4925849-A | DIURETICS, HYPOTENSIVE AGENTS, CARIOTONIC AGENTS AND ANTIEDEMIC AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0299209-A2 | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-18 | — | — | EP | disclosed |