Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205226 | 0.84 | MAPK1 (0.64) | MAPK1CYP1A2NPSR1HSD17B10TSHR | |
| SCHEMBL19537838 | 0.81 | CYP1A2 (0.81) | MAPK1CYP1A2NPSR1HSD17B10TSHR | |
| SCHEMBL9385550 | 0.80 | CYP1A2 (0.73) | MAPK1CYP1A2NPSR1HSD17B10TSHR | |
| SCHEMBL9205218 | 0.79 | MAPK1 (0.72) | MAPK1CYP1A2NPSR1HSD17B10TSHR | |
| SCHEMBL11622591 | 0.79 | MAPK1 (0.72) | MAPK1CYP1A2NPSR1HSD17B10TSHR | |
| SCHEMBL9386259 | 0.79 | MAPK1 (0.72) | MAPK1CYP1A2NPSR1HSD17B10TSHR | |
| SCHEMBL11485825 | 0.79 | SMN1; SMN2 (0.76) | MAPK1CYP1A2NPSR1HSD17B10TSHR | |
| SCHEMBL19538089 | 0.78 | MAPK1 (0.70) | MAPK1CYP1A2NPSR1HSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL9311662 | 0.78 | MAPK1 (0.70) | MAPK1CYP1A2NPSR1HSD17B10TSHR | |
| SCHEMBL7793927 | 0.77 | CYP1A2 (0.73) | MAPK1CYP1A2NPSR1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430693-B1 | Pyrimidinedione derivative compounds, method for preparing same, and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS (JP) | 1995-05-31 | — | — | EP | disclosed |
| US-5114941-A | PYRIMIDINEDIONE DERIVATIVE COMPOUNDS, METHOD FOR PREPARING SAME, AND ANTIARRYTHMIC AGENTS CONTAINING SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0430693-A2 | Pyrimidinedione derivative compounds, method for preparing same, and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-06-05 | — | — | EP | disclosed |