Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712311 | 0.89 | MEN1 (0.58) | KMT2AMEN1PGRHDAC4TP53 | |
| SCHEMBL9287479 | 0.89 | MEN1 (0.58) | KMT2AMEN1PGRHDAC4HIF1A | |
| SCHEMBL10679151 | 0.89 | KMT2A (0.60) | KMT2AMEN1PGRHDAC4TP53 | |
| SCHEMBL9283081 | 0.88 | MEN1 (0.50) | KMT2AMEN1PGRHDAC4TP53 | |
| SCHEMBL9287942 | 0.88 | MEN1 (0.52) | KMT2AMEN1PGRHDAC4HIF1A | |
| SCHEMBL9283154 | 0.88 | MEN1 (0.56) | KMT2AMEN1PGRHDAC4HIF1A | |
| SCHEMBL9267977 | 0.88 | MEN1 (0.56) | KMT2AMEN1PGRHDAC4HIF1A | |
| SCHEMBL9202310 | 0.87 | MEN1 (0.71) | KMT2AMEN1PGRHDAC4TP53 | |
| SCHEMBL9275953 | 0.87 | MEN1 (0.55) | KMT2AMEN1PGRHDAC4HIF1A | |
| SCHEMBL9287103 | 0.87 | MEN1 (0.57) | KMT2AMEN1PGRHDAC4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639182-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992018483-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |