Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 3/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200456 | 1.00 | PTGIR (0.60) | PTGIRFAAHKDM4ETSHRHSD17B10 | |
| SCHEMBL9210200 | 0.89 | PTGIR (0.68) | PTGIRFAAHKDM4ETSHRHSD17B10 | |
| SCHEMBL9771296 | 0.84 | PTGIR (0.82) | PTGIRKDM4ETSHRHSD17B10 | |
| SCHEMBL9208867 | 0.84 | PTGIR (0.82) | PTGIRKDM4ETSHRHSD17B10 | |
| Water SCHEMBL9208617 | 0.83 | PTGIR (0.80) | PTGIRKDM4ETSHRHSD17B10 | |
| Water SCHEMBL9208608 | 0.83 | PTGIR (0.80) | PTGIRKDM4ETSHRHSD17B10 | |
| SCHEMBL9200454 | 0.81 | PTGIR (0.64) | PTGIRFAAHKDM4ETSHRHSD17B10 | |
| SCHEMBL9200446 | 0.81 | PTGIR (0.64) | PTGIRFAAHKDM4ETSHRHSD17B10 | |
| SCHEMBL9206039 | 0.79 | PTGIR (0.77) | PTGIRKDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL9206426 | 0.79 | PTGIR (0.77) | PTGIRKDM4ETSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417449-B1 | Arylpyrazole derivatives as platelet aggregation inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5071866-A | Arylpyrazole derivatives as anti-platelet agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0417449-A1 | Arylpyrazole derivatives as platelet aggregation inhibitors | Bristol-Myers Squibb Company (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4994482-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-02-19 | — | — | US | disclosed |