Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9194002 | 1.00 | HTR2A (0.52) | HTR2ACYP1A2CYP2D6CYP2C19GRIN2D | |
| SCHEMBL8068540 | 1.00 | HTR2A (0.52) | HTR2ACYP1A2CYP2D6CYP2C19GRIN2D | |
| SCHEMBL8976592 | 0.92 | HTR2A (0.52) | HTR2ACYP1A2CYP2D6CYP2C19EPHX1 | |
| Bromide SCHEMBL8209117 | 0.88 | CYP1A2 (0.55) | HTR2ACYP1A2CYP2D6CYP2C19DPP4 | |
| SCHEMBL468022 | 0.85 | EPHX1 (0.61) | CYP1A2CYP2D6CYP2C19GRIN2DGRIN3B | |
| SCHEMBL272604 | 0.85 | EPHX1 (0.61) | CYP1A2CYP2D6CYP2C19GRIN2DGRIN3B | |
| SCHEMBL3451169 | 0.85 | EPHX1 (0.61) | CYP1A2CYP2D6CYP2C19GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL28839661 | 0.83 | EPHX1 (0.58) | CYP1A2CYP2D6CYP2C19GRIN2DGRIN3B | |
| SCHEMBL17887234 | 0.82 | ACP3 (0.51) | CYP1A2CYP2D6CYP2C19GRIN2DGRIN3B | |
| SCHEMBL9322166 | 0.82 | MAOB (0.50) | CYP1A2CYP2D6CYP2C19GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573548-B1 | NEUROPROTECTANT AGENTS | AMERICAN HOME PROD (US) | 1995-07-12 | — | — | EP | disclosed |