Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201160 | 1.00 | ABCG2 (0.42) | ABCG2PTPN1MAOBDPP4CAPN1 | |
| SCHEMBL9203888 | 0.95 | ABCG2 (0.41) | ABCG2PTPN1MAOBDPP4CAPN1 | |
| SCHEMBL9203896 | 0.95 | ABCG2 (0.41) | ABCG2PTPN1MAOBDPP4CAPN1 | |
| SCHEMBL7191098 | 0.90 | ABCG2 (0.51) | ABCG2PTPN1MAOBDPP4CAPN1 | |
| SCHEMBL7191096 | 0.90 | ABCG2 (0.51) | ABCG2PTPN1MAOBDPP4CAPN1 | |
| SCHEMBL7182906 | 0.89 | ABCG2 (0.52) | ABCG2PTPN1MAOBDPP4CAPN1 | |
| SCHEMBL7182909 | 0.89 | ABCG2 (0.52) | ABCG2PTPN1MAOBDPP4CAPN1 | |
| SCHEMBL7180100 | 0.84 | ABCG2 (0.49) | ABCG2PTPN1MAOBDPP4CAPN1 | |
| SCHEMBL7180096 | 0.84 | ABCG2 (0.49) | ABCG2PTPN1MAOBDPP4CAPN1 | |
| SCHEMBL7189009 | 0.83 | ABCG2 (0.50) | ABCG2PTPN1MAOBDPP4CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |