Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.57 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207470 | 0.92 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2 | |
| SCHEMBL9207625 | 0.91 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2 | |
| SCHEMBL9201199 | 0.89 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2 | |
| SCHEMBL9205351 | 0.87 | CYSLTR1 (0.63) | CYSLTR1CYSLTR2 | |
| SCHEMBL9205169 | 0.86 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2 | |
| SCHEMBL9202854 | 0.84 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2 | |
| SCHEMBL9209515 | 0.83 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2 | |
| SCHEMBL9202938 | 0.82 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2 | |
| SCHEMBL9204929 | 0.80 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2 | |
| SCHEMBL9206568 | 0.80 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399818-B1 | Diarylstyrylquinoline diacids | MERCK FROSST CANADA INC (CA) | 1995-08-16 | — | — | EP | disclosed |
| EP-0399818-A1 | Diarylstyrylquinoline diacids | MERCK FROSST CANADA INC. (CA) | 1990-11-28 | — | — | EP | disclosed |
| EP-0318093-A2 | Diarylquinoline diacids and their use as medicaments | MERCK FROSST CANADA INC. (CA) | 1989-05-31 | — | — | EP | disclosed |