⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4695404 | 1.00 | — | — | |
| SCHEMBL17822536 | 1.00 | — | — | |
| SCHEMBL27920507 | 0.81 | CA1 (0.46) | — | |
| SCHEMBL6412244 | 0.80 | CA1 (0.41) | — | |
| SCHEMBL12268 | 0.79 | — | — | |
| SCHEMBL12212 | 0.79 | — | — | |
| SCHEMBL12219 | 0.79 | — | — | |
| SCHEMBL10899562 | 0.79 | — | — | |
| SCHEMBL15116733 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL1372283 | 0.77 | CA1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718637-B2 | Prodrugs of 4′-C-substituted-2-halo-2′- deoxyadenosine nucleosides and methods of making and using the same | GILEAD SCIENCES, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-11718637-B2 | Prodrugs of 4′-C-substituted-2-halo-2′- deoxyadenosine nucleosides and methods of making and using the same | GILEAD SCIENCES, INC. (US) | 2023-08-08 | — | — | US | disclosed |
| EP-4121437-A1 | PRODRUGS OF 4'-C-SUBSTITUTED-2-HALO-2'-DEOXYADENOSINE NUCLEOSIDES AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-01-25 | — | — | EP | disclosed |
| CN-115605493-A | Prodrugs of4'-C-substituted-2-halo-2' -deoxyadenosine nucleosides and methods of making and using the same | 吉利德科学公司（US） | 2023-01-13 | — | — | CN | disclosed |
| US-20220363708-A1 | PRODRUGS OF 4'-C-SUBSTITUTED-2-HALO-2'-DEOXYADENOSINE NUCLEOSIDES AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. | 2022-11-17 | — | — | US | disclosed |
| WO-2021188959-A1 | PRODRUGS OF 4'-C-SUBSTITUTED-2-HALO-2'-DEOXYADENOSINE NUCLEOSIDES AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| EP-0494621-B1 | Substituted alkenoic acid and its derivatives | BAYER AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| US-5246966-A | SUBSTITUTED ALKENOIC ACID AND ITS DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1993-09-21 | — | — | US | disclosed |
| EP-0494621-A1 | Substituted alkenoic acid and its derivatives | BAYER AG (DE) | 1992-07-15 | — | — | EP | disclosed |