Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | APEX1 | P27695 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28576826 | 0.84 | KDM4E (0.73) | KDM4EPOLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL3007153 | 0.83 | KDM4E (0.71) | KDM4EPOLBAPEX1TDP1SMN1; SMN2 | |
| Benzene SCHEMBL28024132 | 0.83 | POLB (1.00) | KDM4EPOLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL3066671 | 0.83 | POLB (1.00) | KDM4EPOLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL29222651 | 0.78 | KDM4E (0.51) | KDM4EPOLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL10516482 | 0.78 | MAPT (0.52) | KDM4EPOLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL28024130 | 0.78 | KDM4E (0.63) | KDM4EPOLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL6966371 | 0.74 | SMN1; SMN2 (1.00) | KDM4EPOLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL1779819 | 0.74 | HTT (0.64) | KDM4EPOLBAPEX1TDP1SMN1; SMN2 | |
| SCHEMBL2453964 | 0.74 | SMN1; SMN2 (0.66) | KDM4EPOLBAPEX1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087780-B2 | Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof | NISSAN CHEMICAL IND LTD (JP) | 1995-02-15 | — | — | EP | disclosed |
| US-4954164-A | Pyrazolesulfonylurea derivatives, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-04 | — | — | US | disclosed |