SCHEMBL9202607

SCHEMBL9202607

COc1cc2cc(C(=O)C(C)CC#N)sc2cc1OC

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 19/20 0.60
ACHE P22303 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20049462 0.83 STING1 (0.65) STING1
SCHEMBL9205580 0.81 STING1 (0.70) STING1
SCHEMBL20022196 0.75 STING1 (0.81) STING1
SCHEMBL20049023 0.75 STING1 (0.60) STING1
SCHEMBL20022200 0.75 STING1 (0.81) STING1
SCHEMBL25015478 0.75 STING1 (1.00) STING1
SCHEMBL20022251 0.75 STING1 (1.00) STING1
SCHEMBL30416864 0.75 STING1 (1.00) STING1
SCHEMBL20022294 0.75 STING1 (1.00) STING1
SCHEMBL21406117 0.74 STING1 (0.79) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350990-B1 Pyridazinone derivatives AKZO NOBEL NV (NL) 1995-09-20 EP disclosed
US-4952571-A Pyridazinone derivatives AKZO, N.V. (NL) 1990-08-28 US disclosed
EP-0350990-A1 Pyridazinone derivatives Akzo Nobel N.V. (NL) 1990-01-17 EP disclosed