Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.69 |
| ▸ | PPARG | P37231 | 3/20 | 0.69 |
| ▸ | PGR | P06401 | 3/20 | 0.69 |
| ▸ | ESR1 | P03372 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.65 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.65 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.65 |
| ▸ | ALB | P02768 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 3/20 | 0.58 |
| ▸ | APAF1 | O14727 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.58 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203209 | 1.00 | NR1I2 (0.69) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL17122849 | 0.93 | NR1I2 (0.72) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL15100211 | 0.93 | NR1I2 (0.72) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL15100223 | 0.93 | NR1I2 (0.72) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL11206803 | 0.91 | NR1I2 (0.72) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9039966 | 0.91 | NR1I2 (0.72) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9039954 | 0.91 | NR1I2 (0.72) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9202264 | 0.90 | NR1I2 (0.71) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9871550 | 0.90 | NR1I2 (0.72) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL9871538 | 0.90 | NR1I2 (0.72) | NR1I2PPARGPGRESR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304155-B1 | Cephalosporin compounds, process for their preparation and their pharmaceutical compositions | ZENECA PHARMA SA (FR) | 1995-11-15 | — | — | EP | disclosed |
| EP-0341948-B1 | Cephalosporins, process for their preparation and pharmaceutical compositions | ICI PLC (GB) | 1995-01-11 | — | — | EP | disclosed |
| EP-0246068-B1 | Process for the manufacture of cephalosporin derivatives | ICI PLC (GB) | 1993-12-08 | — | — | EP | disclosed |
| US-5254679-A | Containing a quaternized nitrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-19 | — | — | US | disclosed |
| EP-0225182-B1 | CEPHALOSPORIN COMPOUNDS | ICI PHARMA (FR) | 1993-02-10 | — | — | EP | disclosed |
| US-5149803-A | Intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-09-22 | — | — | US | disclosed |
| US-5055462-A | CEPHALOSPORIN COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-08 | — | — | US | disclosed |
| US-5049558-A | Quaternized nitrogen-heterocycle substituted | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-17 | — | — | US | disclosed |
| US-5013731-A | Bactericides | ICI PHARMA (FR) | 1991-05-07 | — | — | US | disclosed |
| US-5013730-A | Antibiotics | ICI-PHARMA (FR) | 1991-05-07 | — | — | US | disclosed |
| EP-0164944-B1 | CEPHALOSPORIN DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-07-11 | — | — | EP | disclosed |
| US-4939250-A | Process for preparation of β-lactam derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-07-03 | — | — | US | disclosed |
| EP-0341948-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions | ZENECA LIMITED (GB) | 1989-11-15 | — | — | EP | disclosed |
| EP-0304155-A2 | Cephalosporin compounds, process for their preparation and their pharmaceutical compositions | ZENECA Pharma S.A. (FR) | 1989-02-22 | — | — | EP | disclosed |
| EP-0246068-A2 | Process for the manufacture of cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-11-19 | — | — | EP | disclosed |
| EP-0225182-A2 | Cephalosporin compounds | ICI PHARMA (FR) | 1987-06-10 | — | — | EP | disclosed |
| EP-0164944-A1 | Cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-12-18 | — | — | EP | disclosed |