Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PNLIP | P16233 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PTPRC | P08575 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930039 | 0.86 | DHODH (0.56) | RAB9ASMN1; SMN2NPC1HPGDMAPT | |
| SCHEMBL9197072 | 0.85 | F2R (0.55) | RAB9ASMN1; SMN2NPC1HPGDMAPT | |
| SCHEMBL9199976 | 0.85 | MAPT (0.51) | RAB9ASMN1; SMN2NPC1HPGDMAPT | |
| SCHEMBL8930009 | 0.84 | KCNK3 (0.60) | RAB9ASMN1; SMN2NPC1HPGDMAPT | |
| SCHEMBL27318187 | 0.84 | PPARG (0.53) | RAB9ASMN1; SMN2NPC1MAPTKMT2A | |
| SCHEMBL29376797 | 0.84 | KCNK3 (0.60) | RAB9ASMN1; SMN2NPC1HPGDMAPT | |
| SCHEMBL9198085 | 0.84 | SMN1; SMN2 (0.67) | RAB9ASMN1; SMN2NPC1MAPTKMT2A | |
| SCHEMBL27315886 | 0.82 | KMT2A (0.64) | RAB9ASMN1; SMN2NPC1HPGDMAPT | |
| SCHEMBL8929781 | 0.80 | HPGD (0.58) | RAB9ASMN1; SMN2NPC1HPGDMAPT | |
| SCHEMBL4251978 | 0.80 | NPC1 (0.71) | RAB9ASMN1; SMN2NPC1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497816-B1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD (CA) | 1995-05-17 | — | — | EP | claimed |
| EP-0497816-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN. | UNIROYAL CHEMICAL LTD (CA) | 1992-08-12 | — | — | EP | claimed |
| WO-1991005761-A1 | TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-05-02 | — | — | WO | claimed |
| CN-1051036-A | The treatment of HIV (human immunodeficiency virus) infections and in treatment used compound | UNIROYAL CHEM CO INC (US) | 1991-05-01 | — | — | CN | disclosed |