Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192307 | 0.94 | MAPT (0.47) | DPP4PTPN1MAPTNPC1ALDH1A1 | |
| SCHEMBL7184649 | 0.92 | MAPT (0.49) | DPP4PTPN1MAPTNPC1ALDH1A1 | |
| SCHEMBL7190280 | 0.89 | ABCG2 (0.55) | DPP4PTPN1MAPTNPC1ALDH1A1 | |
| SCHEMBL9197571 | 0.89 | PTPN1 (0.47) | DPP4PTPN1MAPTABCG2 | |
| SCHEMBL7189298 | 0.87 | DPP4 (0.47) | DPP4PTPN1MAPTALDH1A1ABCG2 | |
| SCHEMBL9200658 | 0.87 | DPP4 (0.50) | DPP4PTPN1MAPTALDH1A1ABCG2 | |
| SCHEMBL7192313 | 0.86 | MAPT (0.45) | DPP4PTPN1MAPTNPC1ALDH1A1 | |
| SCHEMBL7186182 | 0.86 | PTPN1 (0.48) | DPP4PTPN1ABCG2BCHEACHE | |
| SCHEMBL9198648 | 0.86 | MAPT (0.45) | DPP4PTPN1MAPTNPC1ALDH1A1 | |
| SCHEMBL9206831 | 0.85 | MAPT (0.43) | DPP4PTPN1MAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |