Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.70 |
| ▸ | CNR1 | P21554 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.65 |
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | CNR2 | P34972 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203398 | 1.00 | EPHX2 (0.70) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL3486532 | 0.90 | EPHX2 (0.79) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL3486455 | 0.90 | EPHX2 (0.79) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL2027629 | 0.90 | EPHX2 (0.79) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL2090537 | 0.90 | EPHX2 (0.79) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL25333433 | 0.90 | EPHX2 (0.79) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL3486141 | 0.90 | EPHX2 (0.79) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL232436 | 0.90 | EPHX2 (0.79) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL3486458 | 0.90 | EPHX2 (0.79) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL43416 | 0.90 | EPHX2 (0.79) | EPHX2CNR1ALDH1A1HPGDSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |