SCHEMBL9203513

SCHEMBL9203513

CCCc1cnccc1N(CCC)n1ccc2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633973 0.92 SLC6A2 (0.65) SLC6A2
SCHEMBL7613274 0.85 SLC6A2 (0.67) SLC6A2
SCHEMBL7609679 0.84 SLC6A2 (0.65) SLC6A2
SCHEMBL7611649 0.84 SLC6A2 (0.65) SLC6A2
Hydrochloric Acid SCHEMBL7610845 0.83 SLC6A2 (0.64) SLC6A2
Hydrochloric Acid SCHEMBL3977692 0.83 SLC6A2 (0.64) SLC6A2
Oxalic Acid SCHEMBL7641771 0.80 SLC6A2 (0.59) SLC6A2
SCHEMBL9796052 0.80 SLC6A2 (0.59) SLC6A2
Besipirdine SCHEMBL637011 0.78 SLC6A2 (1.00) SLC6A2
Besipirdine SCHEMBL31365064 0.78 SLC6A2 (1.00) SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415103-B1 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments HOECHST ROUSSEL PHARMA (US) 1995-02-01 EP disclosed
US-5296488-A Method of using 2,3-dihydro-1-(pyridinylamino)-indoles as anticonvulsants and for the enhancement of memory HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1994-03-22 US disclosed
US-5179099-A Analgesics HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1993-01-12 US disclosed
EP-0415103-A1 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-03-06 EP disclosed