Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 8/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206085 | 1.00 | EPHX1 (0.39) | EPHX1TSHRTHRBALDH1A1GGPS1 | |
| SCHEMBL27743520 | 1.00 | EPHX1 (0.39) | EPHX1TSHRTHRBALDH1A1GGPS1 | |
| SCHEMBL9205901 | 1.00 | EPHX1 (0.39) | EPHX1TSHRTHRBALDH1A1GGPS1 | |
| SCHEMBL2937545 | 1.00 | EPHX1 (0.39) | EPHX1TSHRTHRBALDH1A1GGPS1 | |
| Hydrochloric Acid SCHEMBL28769674 | 0.98 | EPHX1 (0.37) | EPHX1TSHRTHRBALDH1A1GGPS1 | |
| SCHEMBL11416088 | 0.91 | EPHX1 (0.44) | EPHX1TSHRTHRBALDH1A1GGPS1 | |
| SCHEMBL21236821 | 0.91 | EPHX1 (0.44) | EPHX1TSHRTHRBALDH1A1GGPS1 | |
| SCHEMBL8755205 | 0.91 | EPHX1 (0.44) | EPHX1TSHRTHRBALDH1A1GGPS1 | |
| SCHEMBL22623546 | 0.91 | EPHX1 (0.44) | EPHX1TSHRTHRBALDH1A1GGPS1 | |
| SCHEMBL22436200 | 0.91 | EPHX1 (0.39) | EPHX1TSHRTHRBALDH1A1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |