⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196188 | 0.93 | — | — | |
| SCHEMBL9201197 | 0.90 | — | — | |
| SCHEMBL9199255 | 0.89 | — | — | |
| SCHEMBL9200813 | 0.88 | — | — | |
| SCHEMBL9196624 | 0.88 | EDNRB (0.61) | — | |
| SCHEMBL9198187 | 0.88 | — | — | |
| SCHEMBL9199247 | 0.86 | — | — | |
| SCHEMBL9200299 | 0.85 | EDNRB (0.52) | — | |
| SCHEMBL4328034 | 0.84 | — | — | |
| SCHEMBL9204518 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517812-A4 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO INC (US) | 1995-10-18 | — | — | EP | disclosed |
| EP-0517812-A1 | ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-16 | — | — | EP | disclosed |