Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9206462 | 1.00 | PTGIR (0.60) | PTGIRFAAHKMT2ALMNAKDM4E | |
| SCHEMBL9200454 | 0.96 | PTGIR (0.64) | PTGIRFAAHKMT2ALMNAKDM4E | |
| SCHEMBL9200446 | 0.96 | PTGIR (0.64) | PTGIRFAAHKMT2ALMNAKDM4E | |
| SCHEMBL9208810 | 0.89 | PTGIR (0.76) | PTGIRFAAHKMT2ALMNAKDM4E | |
| SCHEMBL9198234 | 0.89 | PTGIR (0.76) | PTGIRFAAHKMT2ALMNAKDM4E | |
| Water SCHEMBL9199653 | 0.88 | PTGIR (0.74) | PTGIRFAAHKMT2ALMNAKDM4E | |
| SCHEMBL9206426 | 0.88 | PTGIR (0.77) | PTGIRKMT2AKDM4ETSHRMEN1 | |
| SCHEMBL9206039 | 0.88 | PTGIR (0.77) | PTGIRKMT2AKDM4ETSHRMEN1 | |
| Water SCHEMBL9200430 | 0.86 | PTGIR (0.76) | PTGIRKMT2AKDM4ETSHRMEN1 | |
| Water SCHEMBL9200450 | 0.86 | PTGIR (0.76) | PTGIRKMT2AKDM4ETSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417449-B1 | Arylpyrazole derivatives as platelet aggregation inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5071866-A | Arylpyrazole derivatives as anti-platelet agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0417449-A1 | Arylpyrazole derivatives as platelet aggregation inhibitors | Bristol-Myers Squibb Company (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4994482-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-02-19 | — | — | US | disclosed |