Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204807 | 1.00 | CA1 (0.43) | CA1CA2KRASKDM4ELMNA | |
| SCHEMBL9203705 | 0.94 | MAOB (0.42) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9203700 | 0.94 | MAOB (0.42) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7183517 | 0.90 | CA1 (0.42) | CA1CA2KRASKDM4ELMNA | |
| SCHEMBL7183516 | 0.90 | CA1 (0.42) | CA1CA2KRASKDM4ELMNA | |
| SCHEMBL7188103 | 0.89 | CA1 (0.52) | CA1CA2KRASKDM4ELMNA | |
| SCHEMBL7188097 | 0.89 | CA1 (0.52) | CA1CA2KRASKDM4ELMNA | |
| SCHEMBL7185369 | 0.86 | CA1 (0.46) | CA1CA2KRASCTSLCTSB | |
| SCHEMBL7185365 | 0.86 | CA1 (0.46) | CA1CA2KRASCTSLCTSB | |
| SCHEMBL7191429 | 0.82 | ABCG2 (0.49) | KDM4ELMNAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |